SCAMP2 Antibody Blocking Peptide

Product Discontinued

SCAMP2 Antibody Blocking Peptide Summary

• Description: SCAMP2 Blocking Peptide corresponds to amino acid residues 1-17 from human SCAMP 2.

  Source: Synthetic

  Amino Acid Sequence: MSAFDTNPFADPVDVNP

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: SCAMP2
• Purity: 100%
• Endotoxin Note: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB120-3431. For further blocking peptide related protocol, click here.
• Theoretical MW: 1.87 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from distilled water.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: 100%
• Reconstitution Instructions: Reconstitute with 0.1 ml of distilled water.

Alternate Names for SCAMP2 Antibody Blocking Peptide

• secretory carrier membrane protein 2secretory carrier-associated membrane protein 2

Background

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for SCAMP2 Protein (NB120-3431PEP)(1)

Publication using NB120-3431PEP

• Jain, P et al. Identification of Human T Cell Leukemia Virus Type 1 Tax Amino Acid Signals Cellular Factors Involved in Secretion of the Viral Oncoprotein. J Biol Chem; 282:34581-34593. 2007-11-01 [PMID: 17897946]

Bioinformatics

• Gene Symbol: SCAMP2