SCAMP2 Products

Antibodies
Lysates
SCAMP2 Overexpression Lysate
SCAMP2 Overexpression Lysate
NBL1-15711
Species: Hu
Applications: WB
Proteins
Recombinant Human SCAMP2 GST ...
Recombinant Human SCAMP2 GST (N-Te...
H00010066-P01
Species: Hu
Applications: WB, ELISA, MA, AP
SCAMP2 Recombinant Protein An ...
SCAMP2 Recombinant Protein Antigen
NBP1-89543PEP
Species: Hu
Applications: AC
SCAMP2 Recombinant Protein An ...
SCAMP2 Recombinant Protein Antigen
NBP1-89552PEP
Species: Hu
Applications: AC

Description

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Product By Gene ID 10066
Alternate Names
  • secretory carrier membrane protein 2secretory carrier-associated membrane protein 2

Research Areas for SCAMP2

Find related products by research area and learn more about each of the different research areas below.

Membrane Trafficking and Chaperones