SCAMP2 Antibody - BSA Free

Western Blot: SCAMP2 Antibody [NB120-3431] - Analysis of SCAMP 2 on AtT20 extract.

Product Discontinued

SCAMP2 Antibody - BSA Free Summary

• Immunogen: Synthetic Peptide: M(1) S A F D T N P F A D P V D V N P(17) C
• Specificity: Detects Secretory Carrier Membrane Protein 2 (SCAMP 2) from mouse testes and AtT20 cell extract, as well as Chinese hamster ovary (CHO) cell extract.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SCAMP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 2 ug/ml
• Application Notes: WB: Detects an approx. 38 kDa protein representing SCAMP 2 from CHO cell extract.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SCAMP2 Antibody - BSA Free

• secretory carrier membrane protein 2secretory carrier-associated membrane protein 2

Background

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SCAMP2 Antibody (NB120-3431)(1)

Publication using NB120-3431

• Jain, P et al. Identification of Human T Cell Leukemia Virus Type 1 Tax Amino Acid Signals Cellular Factors Involved in Secretion of the Viral Oncoprotein. J Biol Chem; 282:34581-34593. 2007-11-01 [PMID: 17897946]

Bioinformatics

• Gene Symbol: SCAMP2
• Entrez:
  • 24044(Mouse)