SAMSN1 Antibody

Images

 
Western Blot: SAMSN1 Antibody [NB300-976] - (1ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

SAMSN1 Antibody Summary

Immunogen
Peptide with sequence IRLDTLSASLGRSC corresponding to N-Terminus according to NP_071419.2.
Specificity
Please note that the immunogen sequence is present in NP_071419.2 (and in AAK07746) but is no longer present in the latest reference sequence (NP_071419.3 at 05/10/05). This latest version has not been subject to final review by NCBI. This antibody may be recognising one particular isoform.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SAMSN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5 - 1.5 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Approx. 48 kDa band observed in Jurkat T cell lysate (calculated MW of 41.7 kDa band according to NP_071419.2). The observed size is consistent with observations with competing products.
Positive Control
SAE2 Lysate (NBL1-17496)
Publications
Read Publications using
NB300-976 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SAMSN1 Antibody

  • HACS1gene with homology to KIAA0790 protein10NASH1
  • Hematopoietic adaptor containing SH3 and SAM domains 1
  • SAM and SH3 domain containing 1
  • SAM and SH3 domain containing 2
  • SAM domain, SH3 domain and nuclear localisation signals, 1
  • SAM domain, SH3 domain and nuclear localization signals 1
  • SAM domain, SH3 domain and nuclear localization signals protein 1
  • SAM domain-containing protein SAMSN-1
  • SH3D6B
  • SH3-SAM adaptor protein

Background

SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung. SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SAMSN1 Antibody (NB300-976)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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WB
(1)
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(1)
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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol SAMSN1
Entrez
Uniprot