Peptide with sequence IRLDTLSASLGRSC corresponding to N-Terminus according to NP_071419.2.
Please note that the immunogen sequence is present in NP_071419.2 (and in AAK07746) but is no longer present in the latest reference sequence (NP_071419.3 at 05/10/05). This latest version has not been subject to final review by NCBI. This antibody may be recognising one particular isoform.
Immunogen affinity purified
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HACS1gene with homology to KIAA0790 protein10NASH1
Hematopoietic adaptor containing SH3 and SAM domains 1
SAM and SH3 domain containing 1
SAM and SH3 domain containing 2
SAM domain, SH3 domain and nuclear localisation signals, 1
SAM domain, SH3 domain and nuclear localization signals 1
SAM domain, SH3 domain and nuclear localization signals protein 1
SAM domain-containing protein SAMSN-1
SH3-SAM adaptor protein
SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung. SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.