S100A10 Antibody (344015) [Alexa Fluor™ Plus 647]

• Reactivity: Mu
• Clone: 344015
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 647

S100A10 Antibody (344015) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects mouse S100A10 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) S100A4, rmS100A8, rmS100A9, recombinant human (rh) S100B, or rhS100P is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for S100A10 Antibody (344015) [Alexa Fluor™ Plus 647]

• annexin II ligand, calpactin I, light polypeptide
• ANX2L
• ANX2LG
• CAL1LGP11,42C
• Calpactin I light chain
• Calpactin-1 light chain
• Cellular ligand of annexin II
• CLP11Ca[1]
• MGC111133
• p10 protein
• p10
• P11
• protein S100-A10
• S100 calcium binding protein A10 (annexin II ligand, calpactin I, lightpolypeptide (p11))
• S100 calcium binding protein A10
• S100 calcium-binding protein A10 (annexin II ligand, calpactin I, lightpolypeptide (p11))
• S100 calcium-binding protein A10
• S100A10

Background

S100A10, also called p11, is a 97 amino acid member of the S100 family of EF hand proteins, but does not bind calcium. It is primarily found, either within or on the surface of mast cells, as a complex of two annexin A2 subunits with two S100A10 subunits. Extracellular S100A10 is a plasminogen receptor important for plasmin production and cellular invasiveness. Intracellular S100A10 may target ligands to the endoplasmic reticulum. Mouse S100A10 shows 92% amino acid identity with human S100A10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.