RSK4 Antibody (SR2252) - BSA Free

Western Blot: RSK4 Antibody (SR2252) [NBP3-22070] - Western blot analysis using NBP3-22070 in SH-SY5Y cell lysate.

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF, IHC
• Clone: SR2252
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

RSK4 Antibody (SR2252) - BSA Free Summary

• Description: Novus Biologicals Rabbit RSK4 Antibody (SR2252) - BSA Free (NBP3-22070) is a recombinant monoclonal antibody validated for use in IHC, WB, Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human RSK4 (Uniprot #: Q9UK32)
• Specificity: Detects endogenous levels of total RSK4
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: RPS6KA6
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:50
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 84 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for RSK4 Antibody (SR2252) - BSA Free

• EC 2.7.11
• EC 2.7.11.1
• p90-RSK 6
• p90RSK6
• pp90RSK4
• PP90RSK4,90 kDa ribosomal protein S6 kinase 6
• ribosomal protein S6 kinase alpha-6
• ribosomal protein S6 kinase, 90kDa, polypeptide 6
• Ribosomal S6 kinase 4
• RPS6KA6
• RSK4
• RSK-4
• RSK4ribosomal protein S6 kinase, 90kD, polypeptide 6
• S6K-alpha 6
• S6K-alpha-6

Background

RSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RPS6KA6