RNF41 Antibody

Product Discontinued

RNF41 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residues 275 and the C-terminus (residue 317) of human Ring Finger Protein 41 using the number given in entry NP_005776.1 (GeneID 10193).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RNF41
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500
  • Immunoprecipitation 5-10 ug/mg lysate
  • Western Blot 1:10000-1:20000
• Application Notes: Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
• Theoretical MW: 36 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  RNF41 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for RNF41 Antibody

• E3 ubiquitin-protein ligase NRDP1
• EC 6.3.2
• EC 6.3.2.-
• FLRF
• MGC45228
• NRDP1
• ring finger protein 41neuregulin receptor degradation protein-1
• SBBI03

Background

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. The specific function of this protein has not yet been determined. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RNF41 Antibody (NB100-583)(2)

Publications using NB100-583

• Pandey R, Bakay M, Hain HS, et al. The Autoimmune Disorder Susceptibility Gene CLEC16A Restrains NK Cell Function in YTS NK Cell Line and Clec16a Knockout Mice. Front Immunol. 2019-02-01 [PMID: 30774629] (WB, Human)
• Pandey R, Bakay M, Hain HS et al. CLEC16A regulates splenocyte and NK cell function in part through MEK signaling. PLoS ONE 2018-09-18 [PMID: 30226884] (WB, Mouse)

FAQs for RNF41 Antibody (NB100-583). (Showing 1 - 1 of 1 FAQs).

1. Does this antibody recognize endogenous protein in IHC?
   • Yes, this antibody is suitable to detect endogenous protein in IHC. This antibody is guaranteed for use in Western Blot, IHC in Paraffin-embedded tissues, IP and proximal ligation assays.

Bioinformatics

• Gene Symbol: RNF41
• Entrez:
  • 10193(Human)
  • 67588(Mouse)
• Uniprot:
  • Q9H4P4(Human)