Rhodopsin Antibody

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Immunohistochemistry-Paraffin: Rhodopsin Antibody [NLS1052] - Analysis of anti-RHO / Rhodopsin antibody with human eye, retina.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Mk, Rb, FeSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Rhodopsin Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from 2nd extracellular domain of human RHO / Rhodopsin.
Specificity
Human RHO / Rhodopsin. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Feline (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RHO
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1 - 3 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Elephant (100%), Zebra finch (100%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Rhodopsin Antibody

  • CSNBAD1
  • MGC138309
  • OPN2MGC138311
  • opsin 2, rod pigment
  • opsin-2
  • retinitis pigmentosa 4, autosomal dominant
  • rhodopsin
  • RP4

Background

Rhodopsin is the first member identified in the Opsin subfamily of GPCRs. Rhodopsin mediates dim-light vision by maximally absorbing light at 495 nm. Mutations in rhodopsin cause retinitis pigmentosa, an inherited disease that initially causes night blindness and loss of the mid-peripheral visual field, and eventually leads to a total loss of vision. Rhodopsin expression has been reported in the rod-shaped photoreceptor cells of the retina.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Blogs on Rhodopsin.

Vision Infographic: Do you see how I see?
Vision involves several parts of the eye processing light which send signals to the brain via the optic nerve to process information. Learn more about the vision process and related ocular proteins in the infographic below. Novus Biological...  Read full blog post.

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Bioinformatics

Gene Symbol RHO
Entrez
Uniprot