RELM beta Antibody [Allophycocyanin]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Allophycocyanin

RELM beta Antibody [Allophycocyanin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse RELM beta
  Gly21-Ala105
  Accession # Q99P86
• Specificity: Detects mouse RELM beta in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant rat RELM gamma is observed and 10% cross-reactivity with recombinant mouse (rm) Resistin and rmRELM alpha is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: RETNLB
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for RELM beta Antibody [Allophycocyanin]

• C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 2
• CCRG
• Colon and small intestine-specific cysteine-rich protein
• Colon carcinoma-related gene protein
• cysteine-rich secreted A12-alpha-like protein 1
• Cysteine-rich secreted protein A12-alpha-like 1
• Cysteine-rich secreted protein FIZZ2
• FIZZ1
• FIZZ2RELM-beta
• found in inflammatory zone 1
• HXCP2XCP2
• RELM beta
• RELMb
• RELMbeta
• resistin like beta
• resistin-like beta
• RETNL2

Background

RELM beta is a family of resistin-like molecules (RELMs) has been identified in rodents and humans. Resistin is a hormone produced by fat cells. RELMalpha is a secreted protein that has a restricted tissue distribution with highest levels in adipose tissue. Another family member, RELMbeta, is a secreted protein expressed only in the gastrointestinal tract, particularly the colon, in both mouse and human. RELMbeta gene expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation. Resistin and the RELMs share a cysteine composition and other signature features. Thus, the RELMs together with resistin comprise a class of tissue-specific signaling molecules. mRELM-alpha should migrate as a monomer under complete reducing conditions. However, it migrates as dimers, trimers, and even higher order multimers under non-reducing conditions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RETNLB