Relaxin-1 Antibody [DyLight 350]

• Reactivity: Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 350

Relaxin-1 Antibody [DyLight 350] Summary

• Immunogen: E. coli-derived recombinant mouse Relaxin-1
  Arg23-Arg54 with an N-terminal Met (B chain) & Glu161-Cys185 (A chain)
  Accession # NP_035402
• Specificity: Detects mouse Relaxin-1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human Relaxin-1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: RLN1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Relaxin-1 Antibody [DyLight 350]

• bA12D24.3.1
• bA12D24.3.2
• H1
• preprorelaxin H1
• prorelaxin H1
• relaxin 1 (H1)
• relaxin 1
• relaxin H1
• Relaxin1
• Relaxin-1
• RLN1
• RLXH1

Background

Relaxin-1 is a protein that is 185 amino acids long, weighs approximately 21 kDa, and has a shorter isoform that is 117 amino acids long and weighs approximately 13 kDa. Relaxin-1 functions as an ovarian hormone that combines with estrogen to produce birth canal dialation as well as remodels connective tissues during pregnancy. Current studies are being done on diseases and disorders relating to this protein including diabetes mellitus, germ cell cancer, pulmonary function, neuroendocrine tumors, cryptorchidism, hepatitis, thyroiditis, breast cancer, hepatitis, hypertension, and cerebritis. Relaxin-1 has also been shown to have interactions with AR, RNF6, and RXFP1 in pathways such as the relaxin, PKC activation, myometrial relaxation and contraction, and androgen receptor signaling pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RLN1