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Relaxin-1 is a protein that is 185 amino acids long, weighs approximately 21 kDa, and has a shorter isoform that is 117 amino acids long and weighs approximately 13 kDa. Relaxin-1 functions as an ovarian hormone that combines with estrogen to produce birth canal dialation as well as remodels connective tissues during pregnancy. Current studies are being done on diseases and disorders relating to this protein including diabetes mellitus, germ cell cancer, pulmonary function, neuroendocrine tumors, cryptorchidism, hepatitis, thyroiditis, breast cancer, hepatitis, hypertension, and cerebritis. Relaxin-1 has also been shown to have interactions with AR, RNF6, and RXFP1 in pathways such as the relaxin, PKC activation, myometrial relaxation and contraction, and androgen receptor signaling pathways.