Reg2 Antibody

• Reactivity: Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Reg2 Antibody Summary

• Immunogen: E. coli-derived recombinant mouse Reg2
  Asp35-Ala173
  Accession # Q08731
• Specificity: Detects mouse Reg2 in direct ELISAs and Western blots. In Western blots, approximately 50% cross-reactivity with recombinant mouse Reg1 is observed and less than 1% cross-reactivity with recombinant human (rh) Reg1B, recombinant rat (rr) Reg2, rrReg3 and rhReg4 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: Reg2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Reg2 Antibody

• Reg2
• regenerating islet-derived 2
• RegII

Background

Mouse Reg2, also known as Lithostathine 2, pancreatic thread protein (PTP2) and pancreatic stone protein 2 (PSP2), is a member of the Reg family of proteins, which are secreted proteins with a C-type lectin domain. Mouse Reg2 is expressed in regenerating islets and normal exocrine pancreas. Mouse Reg2 belongs to the type II subclass of the Reg family and is the only subclass II Reg protein described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Reg2 Antibody (AF2035)(2)

Publications using AF2035

• J Son, W Du, M Esposito, K Shariati, H Ding, Y Kang, D Accili Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of beta-cell failure Nature Communications, 2023-02-02;14(1):558. 2023-02-02 [PMID: 36732513] (IHC, Mouse)
• Sen Guo, Zuo-Zhi Li, Jun Gong, Mei Xiang, Peng Zhang, Guang-Nian Zhao et al. Oncostatin M Confers Neuroprotection against Ischemic Stroke Journal of Neuroscience 2015-08-26 [PMID: 26311783] (Western Blot, Mouse, Rat)

Bioinformatics

• Gene Symbol: Reg2
• Uniprot:
  • Q08731()