REC8 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: REC8 Antibody [29470002] - This image is specific to animal number SDQ0802 1:50000 Affinity Purified
Immunocytochemistry/ Immunofluorescence: REC8 Antibody [29470002] - This image is specific to animal number SDQ0798 1:10000 Affinity Purified, 1:500 Serum
Immunocytochemistry/ Immunofluorescence: REC8 Antibody [29470002] - This image is specific to animal number SDQ0798 1:10,000 Affinity Purified

Product Details

Summary
Product Discontinued
View other related REC8 Primary Antibodies

Order Details


    • Catalog Number
      29470002
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

REC8 Antibody Summary

Immunogen
This antibody was made against a protein fragment from the C Terminus Region
Epitope
MRTEEELENVRRRQKSSLGVQFMRTDDLEEDTRRNRLFEDEERTRDAREDELFFYSSGSLLPNNRLNIHKELLNEAEARYPEWVNFNEFTADHDRKKAAT
Specificity
This product is specific for C. elegans REC8.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
REC8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry
Application Notes
This antibody works in Immunofluorescence (PMID: 22018922). The concentration for this product is lot dependent. Check product vial for current lot concentration. Typically concentration ranges from 0.5 to 1.5 mg/ml. Use in Immunohistochemistry reported in scientific literature (PMID 24367695)
Publications
Read Publications using
29470002 in the following applications:

Reactivity Notes

Caenorhabditis elegans

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

This product was created from the ModEncode Project, a part of the NHGRI, and is sold by SDIX and Novus Biologicals. These C. elegans antibodies were generated in the labs of Jason Lieb, Susan Strome, Julie Ahringer, Arshad Desai, and Abby Dernburg.

Alternate Names for REC8 Antibody

  • Cohesin Rec8p
  • cohesion rec8p
  • HR21spB
  • meiotic recombination and sister chromatid cohesion phosphoprotein of therad21p family
  • meiotic recombination protein REC8 homolog
  • meiotic recombination protein REC8-like 1
  • MGC950
  • REC8 homolog (yeast)
  • REC8L1human homolog of rad21, S. pombe
  • REC8-like 1 (yeast)
  • REC8-like 1
  • Rec8p
  • recombination and sister chromatid cohesion protein homolog

Background

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-20053
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
NB100-330
Species: Hu
Applications: ICC/IF
NB100-207
Species: Hu, Mu, Ce
Applications: WB, IHC, IHC-P, IP
MAB1934
Species: Hu
Applications: WB, Flow, IP, CyTOF-ready
NBP1-58172
Species: Hu, Mu
Applications: WB
NB300-232
Species: Hu, Mu, Rt, Po, Bv, Ch, Fe, Pa
Applications: WB, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
MAB49281
Species: Hu
Applications: Flow, CyTOF-ready
NBP1-58087
Species: Hu, Mu
Applications: WB
NB100-204
Species: Hu, Mu
Applications: WB, Simple Western, ELISA, ICC/IF, IHC, IHC-P, IP
NBP1-89966
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NB100-181
Species: Hu, Mu
Applications: WB, IP
NBP2-75659
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
NBP2-02667
Species: Hu, Rt, Ca, Mk
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NB100-60454
Species: Hu
Applications: IP
NB100-148
Species: Hu, Mu, Rt, Ce, Ch
Applications: WB, ChIP, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vitro, PLA, KD
NBP2-66987
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NB100-91662
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP1-87904
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Supplier Logo

Publications for REC8 Antibody (29470002)(10)

We have publications tested in 1 confirmed species: C. elegans.

We have publications tested in 3 applications: ICC/IF, IHC, MiAr.


Filter By Application
ICC/IF
(4)
IHC
(2)
MiAr
(2)
All Applications
Filter By Species
C. elegans
(5)
All Species
Showing Publications 1 - 10 of 10.
Publications using 29470002 Applications Species
Ellenbecker M, Osterli E, Wang X et al. Dynein Light Chain DLC-1 Facilitates the Function of the Germline Cell Fate Regulator GLD-1 in Caenorhabditis elegans Genetics Dec 3 2018 [PMID: 30509955] (ICC/IF, C. elegans) ICC/IF C. elegans
Hernandez MR, Davis MB, Jiang J et al. Condensin I protects meiotic cohesin from WAPL-1 mediated removal PLoS Genet. May 1 2018 [PMID: 29768402] (ICC/IF, C. elegans) ICC/IF C. elegans
Dawson JA, Methven-Kelley C, Davis GM. atz-1 influences meiosis to maintain germline chromosomal stability in Caenorhabditis elegans Cell Biol. Int. 2017 Jul 11 [PMID: 28696027] (IHC, C. elegans) IHC C. elegans
Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation and Pathway Interconnections with Obesity. Journal of Proteome Research Oct 21 2016 [PMID: 27769113] (MiAr)

Details:
REC8 Antibody used in microarray creation
MiAr
Crawley O, Barroso C, Testori S et al. Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes. Elife. 2016 Feb 04 [PMID: 26841696] (ICC/IF, C. elegans) ICC/IF C. elegans
Severson AF, Meyer BJ. Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes. Elife. 2014 Aug 29 [PMID: 25171895]
Ko S, Kawasaki I, Shim YH. PAB-1, a Caenorhabditis elegans Poly(A)-Binding Protein, Regulates mRNA Metabolism in germline by Interacting with CGH-1 and CAR-1. PLoS One 2013 Dec 19 [PMID: 24367695] (IHC, ICC/IF, C. elegans) IHC, ICC/IF C. elegans
Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. Journal of Proteome Research May 3 2014 [PMID: 23541305] (MiAr)

Details:
Anti-REC8 used in screening array
MiAr
Xu J, Sun X, Jing Y et al. MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells. Cell Res 2012 May [PMID: 22212480]
Harper NC, Rillo R, Jover-Gil S et al. Pairing Centers Recruit a Polo-like Kinase to Orchestrate Meiotic Chromosome Dynamics in C. elegans Developmental Cell. 2011 Oct 19. [PMID: 22018922]

Reviews for REC8 Antibody (29470002) (0)

There are no reviews for REC8 Antibody (29470002). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for REC8 Antibody (29470002) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional REC8 Products

Bioinformatics Tool for REC8 Antibody (29470002)

Discover related pathways, diseases and genes to REC8 Antibody (29470002). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for REC8 Antibody (29470002)

Discover more about diseases related to REC8 Antibody (29470002).
 

Pathways for REC8 Antibody (29470002)

View related products by pathway.

PTMs for REC8 Antibody (29470002)

Learn more about PTMs related to REC8 Antibody (29470002).
 

Research Areas for REC8 Antibody (29470002)

Find related products by research area.

Blogs on REC8

There are no specific blogs for REC8, but you can read our latest blog posts.
Recombinant Monoclonal Antibodies

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our REC8 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol REC8
Uniprot
Novus 100% Guarantee