REC8 Antibody


Immunocytochemistry/ Immunofluorescence: REC8 Antibody [29470002] - This image is specific to animal number SDQ0802 1:50000 Affinity Purified
Immunocytochemistry/ Immunofluorescence: REC8 Antibody [29470002] - This image is specific to animal number SDQ0798 1:10000 Affinity Purified, 1:500 Serum
Immunocytochemistry/ Immunofluorescence: REC8 Antibody [29470002] - This image is specific to animal number SDQ0798 1:10,000 Affinity Purified

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REC8 Antibody Summary

This antibody was made against a protein fragment from the C Terminus Region
This product is specific for C. elegans REC8.
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.


  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry
Application Notes
This antibody works in Immunofluorescence (PMID: 22018922). The concentration for this product is lot dependent. Check product vial for current lot concentration. Typically concentration ranges from 0.5 to 1.5 mg/ml. Use in Immunohistochemistry reported in scientific literature (PMID 24367695)
Read Publications using
29470002 in the following applications:

Reactivity Notes

Caenorhabditis elegans

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
No Preservative
Immunogen affinity purified


This product was created from the ModEncode Project, a part of the NHGRI, and is sold by SDIX and Novus Biologicals. These C. elegans antibodies were generated in the labs of Jason Lieb, Susan Strome, Julie Ahringer, Arshad Desai, and Abby Dernburg.

Alternate Names for REC8 Antibody

  • Cohesin Rec8p
  • cohesion rec8p
  • HR21spB
  • meiotic recombination and sister chromatid cohesion phosphoprotein of therad21p family
  • meiotic recombination protein REC8 homolog
  • meiotic recombination protein REC8-like 1
  • MGC950
  • REC8 homolog (yeast)
  • REC8L1human homolog of rad21, S. pombe
  • REC8-like 1 (yeast)
  • REC8-like 1
  • Rec8p
  • recombination and sister chromatid cohesion protein homolog


This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for REC8 Antibody (29470002)(10)

We have publications tested in 1 confirmed species: C. elegans.

We have publications tested in 3 applications: ICC/IF, IHC, MiAr.

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C. elegans
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Showing Publications 1 - 10 of 10.
Publications using 29470002 Applications Species
Ellenbecker M, Osterli E, Wang X et al. Dynein Light Chain DLC-1 Facilitates the Function of the Germline Cell Fate Regulator GLD-1 in Caenorhabditis elegans Genetics Dec 3 2018 [PMID: 30509955] (ICC/IF, C. elegans) ICC/IF C. elegans
Hernandez MR, Davis MB, Jiang J et al. Condensin I protects meiotic cohesin from WAPL-1 mediated removal PLoS Genet. May 1 2018 [PMID: 29768402] (ICC/IF, C. elegans) ICC/IF C. elegans
Dawson JA, Methven-Kelley C, Davis GM. atz-1 influences meiosis to maintain germline chromosomal stability in Caenorhabditis elegans Cell Biol. Int. 2017 Jul 11 [PMID: 28696027] (IHC, C. elegans) IHC C. elegans
Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation and Pathway Interconnections with Obesity. Journal of Proteome Research Oct 21 2016 [PMID: 27769113] (MiAr)

REC8 Antibody used in microarray creation
Crawley O, Barroso C, Testori S et al. Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes. Elife. 2016 Feb 04 [PMID: 26841696] (ICC/IF, C. elegans) ICC/IF C. elegans
Severson AF, Meyer BJ. Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes. Elife. 2014 Aug 29 [PMID: 25171895]
Ko S, Kawasaki I, Shim YH. PAB-1, a Caenorhabditis elegans Poly(A)-Binding Protein, Regulates mRNA Metabolism in germline by Interacting with CGH-1 and CAR-1. PLoS One 2013 Dec 19 [PMID: 24367695] (IHC, ICC/IF, C. elegans) IHC, ICC/IF C. elegans
Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. Journal of Proteome Research May 3 2014 [PMID: 23541305] (MiAr)

Anti-REC8 used in screening array
Xu J, Sun X, Jing Y et al. MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells. Cell Res 2012 May [PMID: 22212480]
Harper NC, Rillo R, Jover-Gil S et al. Pairing Centers Recruit a Polo-like Kinase to Orchestrate Meiotic Chromosome Dynamics in C. elegans Developmental Cell. 2011 Oct 19. [PMID: 22018922]

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