RCC1 Antibody (3D11) [Janelia Fluor® 646]

Product Discontinued

RCC1 Antibody (3D11) [Janelia Fluor® 646] Summary

• Immunogen: Recombinant human RanGEF.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RCC1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Recognizes Human, Mouse and Rat RanGEF. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for RCC1 Antibody (3D11) [Janelia Fluor® 646]

• Cell cycle regulatory protein
• CHC1RCC1-I
• chromosome condensation 1
• Chromosome condensation protein 1
• guanine nucleotide-releasing protein
• regulator of chromosome condensation 1
• regulator of chromosome condensation
• SNHG3-RCC1 readthrough transcript
• SNHG3-RCC1

Background

Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensationin the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of asignal transmission pathway that detects unreplicated DNA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RCC1