RBBP6 Antibody


Immunoprecipitation: RBBP6 Antibody [NBP1-49542] - Immunoprecipitation of RbBP6 from HeLa cells using A. NBP1-49542 and B. NBP1-49535.

Product Details

Reactivity Hu, MouseSpecies Glossary
Applications WB, IP
1 mg/ml

RBBP6 Antibody Summary

A synthetic peptide made to an internal portion of the human RBBP6 protein (between residues 20-70) [UniProt Q7Z6E9]
Nucleus nucleolus. Chromosome. Note: Colocalizes with mitotic chromosomes.
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.05% Sodium Azide
1 mg/ml
Immunogen affinity purified


  • Western Blot 1:100-1:2000
  • Immunoprecipitation 1:10-1:500
Application Notes
This RBBP6 antibody is useful for immunoprecipitation.

Reactivity Notes

Human. Predicted to react with mouse based on 100% sequence homology.

Alternate Names for RBBP6 Antibody

  • E3 ubiquitin-protein ligase RBBP6
  • EC 6.3.2.-
  • MY038
  • P2PR
  • P2P-R
  • p53-associated cellular protein of testis
  • PACTDKFZp761B2423
  • Proliferation potential-related protein
  • Protein P2P-R
  • RB-binding Q-protein 1
  • RBQ1
  • RBQ-1
  • retinoblastoma binding protein 6
  • Retinoblastoma-binding protein 6DKFZp686P0638
  • Retinoblastoma-binding Q protein 1


RBBP6 (retinoblastoma binding protein 6; P2PR, PACT, RBQ1) is a multidomain protein with an expected molecular size of about 250kD and it colocalizes with mitotic chromosomes as well as with NEK6 in centrosomes. RBBP6 is highly expressed in normal placenta and testis, and is overexpressed in certain cancers (esophageal and lung cancer). RBBP6 is a multifunctional protein which is found presumably in all eukaryotes and is implicated in versatile cellular activities such as mRNA metabolism, cell cycle regulation, carcinogenesis, and development. It forms part of the pre-mRNA 3-end processing complex in humans and the cleavage/polyadenylation factor complex in yeast. RBBP6 interacts with p53/TP53, RB1, NEK6, MDM2, YBX1 etc., and gets phosphorylated upon DNA damage via ATM/ATR or through NEK6. RBBP6 is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, thereby facilitating its proteasomal degradation. RBBP6 also acts as a scaffold protein to enhance the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53, thereby acting as a negative regulator of p53/TP53.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, Simple Western, IP, ICC
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IF
Species: Hu, Mu, Rt
Applications: WB
Species: Hu
Applications: WB
Species: Hu, Eq, Pm
Applications: WB, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu, Rt
Applications: WB, ChIP, ELISA, ICC/IF, IHC, IHC-P, IP, RNAi, S-ELISA
Species: Hu
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Ca, Pm
Applications: WB
Species: Hu, Mu, Rt, Pm, Rb, Sh
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu, Rt
Applications: WB
Species: Hu
Applications: WB, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP
Species: Hu
Applications: WB, ELISA, PA

Publications for RBBP6 Antibody (NBP1-49542) (0)

There are no publications for RBBP6 Antibody (NBP1-49542).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for RBBP6 Antibody (NBP1-49542) (0)

There are no reviews for RBBP6 Antibody (NBP1-49542). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for RBBP6 Antibody (NBP1-49542) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP1-49542AF405
Alexa Fluor (R) 488 Labeled NBP1-49542AF488
Alexa Fluor (R) 647 Labeled NBP1-49542AF647
Alexa Fluor (R) 700 Labeled NBP1-49542AF700
Biotin Labeled NBP1-49542B
DyLight 405 Labeled NBP1-49542V
DyLight 488 Labeled NBP1-49542G
DyLight 550 Labeled NBP1-49542R
DyLight 650 Labeled NBP1-49542C
FITC Labeled NBP1-49542F
HRP Labeled NBP1-49542H

Additional RBBP6 Antibody Products

Related Products by Gene

Bioinformatics Tool for RBBP6 Antibody (NBP1-49542)

Discover related pathways, diseases and genes to RBBP6 Antibody (NBP1-49542). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for RBBP6 Antibody (NBP1-49542)

Discover more about diseases related to RBBP6 Antibody (NBP1-49542).

Pathways for RBBP6 Antibody (NBP1-49542)

View related products by pathway.

PTMs for RBBP6 Antibody (NBP1-49542)

Learn more about PTMs related to RBBP6 Antibody (NBP1-49542).

Research Areas for RBBP6 Antibody (NBP1-49542)

Find related products by research area.

Blogs on RBBP6

There are no specific blogs for RBBP6, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol RBBP6

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-49542 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought