Western Blot: RBBP4/RbAp48 Antibody [NB100-60399] - Whole cell lysate from HeLa (5, 15, and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), and mouse NIH3T3 (M; 50 ug) cells. Antibodies: NB100-60399 ...read more
Immunohistochemistry-Paraffin: RBBP4/RbAp48 Antibody [NB100-60399] - FFPE section of human Ewing sarcoma. Antibody: Affinity purified rabbit anti-RBBP4/RbAp48 used at a dilution of 1:200 (1ug/ml).Detection: DAB
Immunohistochemistry-Paraffin: RBBP4/RbAp48 Antibody [NB100-60399] - FFPE section of human bladder cell carcinoma. Antibody used at a dilution of 1:500.
Proximity Ligation Assay: RBBP4/RbAp48 Antibody [NB100-60399] - The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic ...read more
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human retinoblastoma binding protein 4 (retinoblastoma-binding protein p48) using the numbering given in entry CAA52321.1 (GeneID 5928).
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NB100-60399 in the following applications:
Based on 100% sequence identity, this antibody is predicted to react with X. laevis, X. tropicalis, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Atlantic salmon, White-tufted-ear marmoset and Northern white-cheeked gibbon.
Alternate Names for RBBP4/RbAp48 Antibody
CAF-1 subunit C
Chromatin assembly factor 1 subunit C
Chromatin assembly factor I p48 subunit
chromatin assembly factor/CAF-1 p48 subunit
histone-binding protein RBBP4
MSI1 protein homolog
Nucleosome-remodeling factor subunit RBAP48
retinoblastoma binding protein 4
Retinoblastoma-binding protein 4CAF-I 48 kDa subunit
Retinoblastoma-binding protein p48
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.