RB1CC1 Antibody

Images

 
Independent Antibodies: Western Blot: RB1CC1 Antibody [NB100-77279] - Detection of Human FIP200/RB1CC1 on HeLa whole cell lysate using NB100-77279. FIP200/RB1CC1 was also immunoprecipitated by rabbit ...read more
Western Blot: RB1CC1 Antibody [NB100-77279] - Whole cell lysate from TCMK-1 (15 and 50 ug) cells. Antibodies: Affinity purified rabbit anti-FIP200/RB1CC1 antibody used for WB at 0.2 ug/ml. Detection: Chemiluminescence ...read more
Western Blot: RB1CC1 Antibody [NB100-77279] - Detection of Mouse FIP200/RB1CC1 by Western Blot. Samples: Whole cell lysate from TCMK-1 (15 and 50 ug) cells. Antibodies: Affinity purified rabbit anti-FIP200/RB1CC1 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

RB1CC1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1544 and 1594 of human 200 kDa FAK family kinase-interacting protein (RB1-inducible coiled-coil 1) using the numbering given in entry NP_055596.2 (GeneID 9821).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RB1CC1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Theoretical MW
183 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
RB1CC1 Lysate (NBL1-15184)
Publications
Read Publications using
NB100-77279 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RB1CC1 Antibody

  • CC1
  • DRAGOU14
  • FIP200
  • KIAA0203200 kDa FAK family kinase-interacting protein
  • RB1-inducible coiled-coil 1
  • RB1-inducible coiled-coil protein 1
  • RBICC

Background

FIP200 (FAK-family interacting protein of 200 kDa) appears to play several key roles related to cell growth, proliferation, development, and tumorigenesis. FIP200 was originally identified in a yeast two-hybrid screen for Pyk2 kinase interacting proteins. It was later identified as a protein that interacts with FAK (focal adhesion kinase), a signal transducing protein that mediates signals from the extracellular matrix to the cytoskeleton to influence cell motility, and cell cycle progression. FIP200 is also known as RB1CC1 (RB1-inducible coiled-coil 1) and has been found to function as a regulator of the retinoblastoma 1 (RB1) tumor suppressor. FIP200 associates with the tumor suppressor TSC1 which partners with TSC2 to antagonize the mTOR signaling pathway. FIP200 association with TSC2 promotes mTOR activity by interfering with the antagonistic effects of the TSC1-TSC2 complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for RB1CC1 Antibody (NB100-77279)(3)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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WB
(1)
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Control Lysate(s)

Secondary Antibodies

 

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Blogs on RB1CC1.

Autophagy independent roles of the core ATG proteins
By Christina Towers, PhD. Autophagy and ATG ProteinsAutophagy is a nutrient recycling process that cells use to fuel metabolism, particularly in response to nutrient deprivation.  It is critical for removal of dam...  Read full blog post.

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Bioinformatics

Gene Symbol RB1CC1
Entrez
Uniprot