RASA4 Antibody

Images

 
Western Blot: RASA4 Antibody [NBP2-15089] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa 7. 5% SDS PAGE, antibody diluted at 1:3000.
Immunocytochemistry/ Immunofluorescence: RASA4 Antibody [NBP2-15089] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.9 mg/ml

Order Details

RASA4 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human RASA4. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RASA4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.9 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RASA4 Antibody

  • Ca2+-promoted Ras inactivator
  • Calcium-promoted Ras inactivator
  • CAPRIGAPLKIAA0538RASA4B
  • FLJ59070
  • Putative Ras GTPase-activating protein 4B
  • ras GTPase-activating protein 4
  • RAS p21 protein activator 4MGC131890
  • RasGAP-activating-like protein 2

Background

This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for RASA4 Antibody (NBP2-15089) (0)

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Secondary Antibodies

 

Isotype Controls

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RASA4 NBP2-15089

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Bioinformatics

Gene Symbol RASA4