RAP1A Antibody

Product Discontinued

RAP1A Antibody Summary

• Immunogen: Synthetic peptide corresponding to the N-terminus of human Rap1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RAP1A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Application Notes: This antibody is useful in Western Blot (Detects a band of ~25kDa).

Reactivity Notes

Recognizes Human, Mouse and Rat Rap1.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for RAP1A Antibody

• C21KG
• G-22K
• GTP-binding protein smg p21A
• KREV-1
• KREV1Ras-related protein Krev-1
• RAP1
• Rap1A
• RAP1A, member of RAS oncogene family
• RAS-related protein RAP1A
• ras-related protein Rap-1A
• SMGP21

Background

Rap1, which is a member of the Ras family of GTP-binding proteins, cycles between an active GTP-bound and an unactive GDP-bound form that is mediated by GTPase activating protein (GAP). Rap1 is proposed to regulate Ras-mediated signaling and may also be involved in the regulation of Integrin-mediated cell adhesion although the mechanism of regulation is not known.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RAP1A Antibody (NBP1-97489)(1)

Publication using NBP1-97489

• Dumbacher M, Van Dooren T, Princen K et al. Modifying Rap1-signalling by targeting Pde6d is neuroprotective in models of Alzheimer's disease. Mol Neurodegener 2018-09-26 [PMID: 30257685] (WB, Mouse)

Bioinformatics

• Gene Symbol: RAP1A