Rab11A Antibody

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Western Blot: Rab11A Antibody [NB120-3612] - Analysis of PC3 cell extract.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Rab11A Antibody Summary

Immunogen
Synthetic peptide corresponding to residues M(1) G T R D D E Y D Y L F K V V L I C(17) of human Rab11.
Localization
Located on the cytoplasmic face of organelles and vesicles.
Marker
Recycling Endosome Marker
Specificity
NB120-3612 detects Rab 11 from human and non-human primate samples.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RAB11A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 6.6 ug/ml
Application Notes
WB: Detects an approx. 22 kDa protein representing Rab 11 in CV1, PC3, and HeLa cell extract. Another less prominent, unknown band is also detected by this antibody at approx. 35 kDa.

Reactivity Notes

Expected cross-reactivity with Rat and Mouse base on sequence homology.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Rab11A Antibody

  • MGC1490
  • RAB 11A, member oncogene family
  • RAB11
  • Rab-11
  • Rab11A
  • RAB11A, member RAS oncogene family
  • YL8
  • YL8ras-related protein Rab-11A

Background

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RAB11A
Entrez