QDPR Antibody [DyLight 405]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 405

QDPR Antibody [DyLight 405] Summary

• Immunogen: E. coli-derived recombinant human QDPR
  Ala2-Phe244
  Accession # P09417
• Specificity: Detects human, mouse, and rat QDPR in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: QDPR
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for QDPR Antibody [DyLight 405]

• DHPR member 1
• DHPR
• HDHPR
• PKU2
• QDPR
• quinoid dihydropteridine reductaseFLJ42391
• SDR33C1

Background

QDPR encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: QDPR