PTPRN2 293T Cell Transient Overexpression Lysate

Product Discontinued

PTPRN2 293T Cell Transient Overexpression Lysate Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-PTPRN2 antibody by Western Blots. Plasmid: pCMV-PTPRN2 full-length
• Specificity: PTPRN2 293T Cell Transient Overexpression Lysate(Denatured)
• Gene: PTPRN2

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

• Type: 293T Cell Transient Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PTPRN2 293T Cell Transient Overexpression Lysate

• EC 3.1.3.48
• IA-2beta
• IAR/receptor-like protein-tyrosine phosphatase
• ICAARIARPTPRP
• Islet cell autoantigen-related protein
• KIAA0387
• phogrin
• protein tyrosine phosphatase receptor pi
• protein tyrosine phosphatase, receptor type, N polypeptide 2
• receptor-type tyrosine-protein phosphatase N2
• R-PTP-N2
• tyrosine phosphatase IA-2 beta

Background

PTPRN2 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PTPRN2