PTPRN2 Antibody Pair

Product Discontinued

PTPRN2 Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-PTPRN2 (300 ul)
• Antibody pair for WB: mouse purified polyclonal anti-PTPRN2 (50 ug)
• Clonality: Polyclonal
• Gene: PTPRN2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PTPRN2 Antibody Pair

• EC 3.1.3.48
• IA-2beta
• IAR/receptor-like protein-tyrosine phosphatase
• ICAARIARPTPRP
• Islet cell autoantigen-related protein
• KIAA0387
• phogrin
• protein tyrosine phosphatase receptor pi
• protein tyrosine phosphatase, receptor type, N polypeptide 2
• receptor-type tyrosine-protein phosphatase N2
• R-PTP-N2
• tyrosine phosphatase IA-2 beta

Background

PTPRN2 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PTPRN2