Immunohistochemistry-Paraffin: PTP alpha/PTPRA Antibody [NLS6792] - Anti-PTPRA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: PTP alpha/PTPRA Antibody [NLS6792] - Analysis of anti-PTPRA antibody with human heart at dilution 10 ug/ml.
Hu, Mu, Po, Bt, Bv, Ca, Eq, Ha, Mk, Pm, Rb, RtSpecies Glossary
Gorilla, Gibbon, Marmoset. Predicted cross-rectivity based on sequence identity: Panda (100%), Elephant (88%), Turkey (88%), Chicken (88%), Xenopus (82%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for PTP alpha/PTPRA Antibody
protein tyrosine phosphatase, receptor type, A
Protein-tyrosine phosphatase alpha
PTPAreceptor type, alpha polypeptide
receptor-type tyrosine-protein phosphatase alpha
tyrosine phosphatase alpha
PTP alpha, a R4 receptor protein tyrosine phosphatase, is implicated in neuron formation, retinal development, cell adhesion, potassium channel regulation, nerve repair, insulin signaling, and cell cycle regulation. PTP alpha activates the Src protein tyrosine kinase during mitosis, resulting in the transition from G2 to mitosis in the cell cycle. PTP alpha is associated with carcinomas of breast, colon, oral squamous cell and prostate. A cytosolic form of PTP alpha, p66 PTP alpha, has recently been isolated. p66 PTP alpha is produced by calpain-mediated proteolytic cleavage and its expression has been detected in nearly all cell types where PTP alpha is expressed. PTP alpha expression has been documented in human neoplastic breast, colon, prostate, and oral tissues, as well as in normal adipose, liver, skeletal muscle, and endothelial cells. ESTs have been isolated from a diverse set of normal and cancerous tissue libraries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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