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Proteinase 3/Myeloblastin/PRTN3 Antibody (1B10)

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Summary
Product Discontinued
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    • Catalog Number
      NB200-423
    • Availability
      Product Discontinued

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Proteinase 3/Myeloblastin/PRTN3 Antibody (1B10) Summary

Immunogen
Human proteinase PR3 purified leukocyte mass.
Specificity
NB200-423 and NB200-424 detect different determinants of proteinase PR3 which have not been fully determined.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PRTN3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Proteinase 3/Myeloblastin/PRTN3 Antibody (1B10)

  • ACPA
  • AGP7
  • AGP7PR3
  • azurophil granule protein 7
  • C-ANCA
  • EC 3.4.21
  • EC 3.4.21.76
  • Leukocyte proteinase 3
  • MBN
  • MBT
  • Myeloblastin
  • Neutrophil proteinase 4
  • NP4
  • NP-4
  • P29C-ANCA antigen
  • PR-3CANCA
  • Proteinase 3
  • PRTN3
  • serine proteinase, neutrophil
  • Wegener autoantigen
  • Wegener granulomatosis autoantigen

Background

Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. PR3 plays a role in neutrophil response to inflammation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Proteinase
3/Myeloblastin/PRTN3 ...
NB200-423
Proteinase 3/Myeloblastin/PRTN3 Antibody (1B10)
Species: Hu
Applications: WB, ELISA

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Bioinformatics

Gene Symbol PRTN3
Entrez