Western Blot: PRMT5 Antibody [NB100-56641] - Western blot analysis of PRMT5 in cell lysates from HeLa cells using NB100-56641 at 1:500. Twenty microgram of HeLa cell lysate was loaded per well of a mini gel.
Western Blot: PRMT5 Antibody [NB100-56641] - analysis of PRMT5 in A) human HeLa and B) mouse NIH 3T3 lysate using this antibody.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.1 mg/ml BSA.
0.02% Sodium Azide
Protein G purified
Alternate Names for PRMT5 Antibody
Histone-arginine N-methyltransferase PRMT5
HMT1 hnRNP methyltransferase-like 5,72 kDa ICln-binding protein
Jak-binding protein 1
protein arginine methyltransferase 5
protein arginine N-methyltransferase 5
Shk1 kinase-binding protein 1 homolog
skb1 (S. pombe) homolog
SKB1 homolog (S. pombe)
Protein arginine methylation is an important posttranslational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT5, also known as Janus kinase-binding protein 1 (JBP1) and Skb1Hs (human homolog of Skb1 of fission yeast can catalyze the formation of omega-N(G)-monomethylarginine and symmetric omega-N(G), N(G')-dimethylarginine in a variety of proteins. Recombinant PRMT5 can mono and dimethylate histone 2A and myelin basic protein. PRMT5 appears to have lower specific enzyme activity than PRMT1.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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