PRMT5 Products

Antibodies
PRMT5 Antibody (2H3)
PRMT5 Antibody (2H3)
Species: Hu
Applications: IHC
Host: Mouse monoclonal
PRMT5 Antibody
PRMT5 Antibody
NB100-56641
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
PRMT5 Antibody
PRMT5 Antibody
NBP1-81701
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PRMT5 Overexpression Lysate ( ...
PRMT5 Overexpression Lysate (Denat...
H00010419-T01
Species: Hu
Applications: WB
PRMT5 Overexpression Lysate ( ...
PRMT5 Overexpression Lysate (Native)
NBL1-14795
Applications: WB
Proteins
PRMT5 Recombinant Protein
PRMT5 Recombinant Protein
H00010419-P01
Species: Hu
Applications: WB, ELISA, PA
PRMT5 Partial Recombinant Pro ...
PRMT5 Partial Recombinant Protein
H00010419-Q01
Species: Hu
Applications: WB, ELISA, PA
PRMT5 Recombinant Protein Ant ...
PRMT5 Recombinant Protein Antigen
NBP1-81701PEP
Species: Hu
Applications: AC

Description

Arginine methylation is an irreversible post translational modification linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins (Histone 2A, 3, 4), IL enhancer binding factor, nuclear factors (NF45, 90, ILF3, Nucleolin, STAT1, Poly(A) binding protein II), cell cycle proteins (phosphoprotein phosphatase 2A), signal transduction proteins (FGF2, Fibrillarin, FN, INFAR1, Jak, MBP, Src-adaptor Sam68), apoptosis proteins (FADD, ICE-like protease), and viral proteins (Hepatitis C NS3 RNA Helicase, HIV TAR). The mammalian PRMT family currently consists of 5 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all five PRMT members have been developed. These antibodies can be utilized to explore arginine methylation and its regulatory functions.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 10419
Alternate Names
  • JBP1
  • EC 2.1.1.125
  • IBP72
  • EC 2.1.1.-
  • HRMT1L5
  • protein arginine N-methyltransferase 5
  • HMT1 hnRNP methyltransferase-like 5,72 kDa ICln-binding protein
  • Shk1 kinase-binding protein 1 homolog
  • SKB1 homolog (S. pombe)
  • Jak-binding protein 1
  • skb1 (S. pombe) homolog
  • Histone-arginine N-methyltransferase PRMT5
  • SKB1HsSKB1 homolog
  • SKB1
  • protein arginine methyltransferase 5

Research Areas for PRMT5

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Chromatin Research
Circadian Rhythm

Bioinformatics Tool for PRMT5

Discover related pathways, diseases and genes to PRMT5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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