PP1 Antibody (319319) [Alexa Fluor® 488]

• Applications: WB
• Clone: 319319
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

PP1 Antibody (319319) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human PP1α catalytic subunit
  Lys41-Pro298
  Accession # P62136
• Specificity: Detects endogenous human, mouse and rat PP1 alpha . Based on the amino acid homologies, the antibody is expected to cross‑react with PP1 beta and PP1 gamma .
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Protein Phosphatase 1, also known as PP1 and PPP1, is an enzyme that removes phosphate groups attached to serine or threonine residues in proteins. The holoenzyme is composed of two subunits, a catalytic subunit (PP1ca) that is highly conserved throughout evolution, and a wide variety of regulatory subunits that target the enzyme to specific subcellular compartments and proteins. The catalytic subunit is ubiquitously expressed in tissues and cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.