PP1 Antibody (319319) [Alexa Fluor™ Plus 680] Summary
| Specificity |
Detects endogenous human, mouse and rat PP1 alpha . Based on the amino acid homologies, the antibody is expected to cross‑react with PP1 beta and PP1 gamma . |
| Isotype |
IgG2a |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Packaging, Storage & Formulations
| Storage |
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
| Buffer |
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Background
Protein Phosphatase 1, also known as PP1 and PPP1, is an enzyme that removes phosphate groups attached to serine or threonine residues in proteins. The holoenzyme is composed of two subunits, a catalytic subunit (PP1ca) that is highly conserved throughout evolution, and a wide variety of regulatory subunits that target the enzyme to specific subcellular compartments and proteins. The catalytic subunit is ubiquitously expressed in tissues and cell lines.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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