Potassium Channel Kv2.2 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: Potassium Channel Kv2.2 Antibody [NBP2-57427] - Staining of human cell line HaCaT shows localization to nucleoli, plasma membrane & centrosome.

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Potassium Channel Kv2.2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Potassium Channel Kv2.2 Antibody - BSA Free (NBP2-57427) is a polyclonal antibody validated for use in ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QHISTILLEETPSQGDRPLLGTEVSAPCQGPSKGLSPRFPKQKLFPFSSRERRSFTEIDTGDDEDFLELP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNB2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
• Application Notes: Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  Potassium Channel Kv2.2 Recombinant Protein Antigen (NBP2-57427PEP)

Reactivity Notes

Rat 81%

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Potassium Channel Kv2.2 Antibody - BSA Free

• delayed rectifier potassium channel protein
• KCNB2
• KV2.2
• Potassium Channel Kv2.2
• potassium voltage-gated channel subfamily B member 2
• potassium voltage-gated channel, Shab-related subfamily, member 2
• voltage-gated potassium channel subunit Kv2.2

Background

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNB2