Species: Rt, Xp
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996).
Bioinformatics
Entrez |
Rat Human |
Uniprot |
Rat |
Product By Gene ID |
9312 |
Alternate Names |
- delayed rectifier potassium channel protein
- KV2.2
- potassium channel Kv2.2
- potassium voltage-gated channel subfamily B member 2
- potassium voltage-gated channel, Shab-related subfamily, member 2
- voltage-gated potassium channel subunit Kv2.2
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