PLC-delta 3 Antibody [DyLight 350]

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 350

PLC-delta 3 Antibody [DyLight 350] Summary

• Immunogen: E. coli-derived recombinant human PLC‑δ3
  Lys148-Ala344
  Accession # Q8N3E9
• Specificity: Detects human and mouse PLC‑δ3 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PLCD3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PLC-delta 3 Antibody [DyLight 350]

• EC 3.1.4.11
• KIAA1964
• MGC71172
• Phosphoinositide phospholipase C-delta-3
• phospholipase C, delta 3,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3
• Phospholipase C-delta-3
• PLC delta3
• PLCD3
• PLCdelta 3
• PLC-delta 3
• PLC-delta-3

Background

PLCD3, also referred to as Phospholipase C-delta-3, is 789 amino acids in length and approximately 89kDa. PLCD3 is a member of the Phospholipase C family and functions to hydrolyze PIP2 to produce the second messangers DAG and IP3. Current research on PLCD3 is being conducted in relation to several diseases and disorders including breast cancer, glioblastoma, Huntington's disease and neurological diseases. PLCD3 has also been shown to have interactions with ITPR1, ITPR3, PIK3C3, DGKE and SKIL in pathways such as the CREB pathway, sweet taste signaling and Inositol phosphate metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLCD3