Rat Plasminogen ELISA Kit (Chemiluminescence)

ELISA: Rat Plasminogen ELISA Kit (Chemiluminescence) [NBP2-68099] - Samples were spiked with high concentrations of Rat Plasminogen and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Rat Plasminogen ELISA Kit (Chemiluminescence) [NBP2-68099] - Standard Curve Reference

• Reactivity: Rt
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 1.56-100 ng/mL
• Sensitivity: 0.94 ng/mL

Rat Plasminogen ELISA Kit (Chemiluminescence) Summary

• Specificity: This kit recognizes Rat Plg in samples. No significant cross-reactivity or interference between Rat Plg and analogues was observed.
• Standard Curve Range: 1.56-100 ng/mL
• Sensitivity: 0.94 ng/mL
• Assay Type: Sandwich-CLIA
• Inter-Assay: CV% < 8.73%
• Intra-Assay: CV% < 9.1%
• Spike Recovery: 90-117%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Chemiluminescence)
• Gene: PLG

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Rat Plasminogen ELISA Kit (Chemiluminescence)

• DKFZp779M0222
• EC 3.4.21
• EC 3.4.21.7
• plasmin
• Plasminogen
• Plg

Background

Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 to 200mg/L. Plasminogen is activated by tissue plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PLG