PIG3 Antibody

Images

 
Western Blot: PIG3 Antibody [H00009540-D01P] - Analysis of TP53I3 expression in transfected 293T cell line by TP53I3 polyclonal antibody.Lane 1: TP53I3 transfected lysate(35.50 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PIG3 Antibody Summary

Immunogen
TP53I3 (NP_004872.2, 1 a.a. ~ 332 a.a) full-length human protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TP53I3
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
This antibody is useful for Western Blot

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PIG3 Antibody

  • p53-induced gene 3 protein
  • PIG3quinone oxidoreductase homolog
  • quinone oxidoreductase PIG3
  • tumor protein p53 inducible protein 3
  • Tumor protein p53-inducible protein 3

Background

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TP53I3
Uniprot