PIEZO1 Antibody (1081418) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 1081418
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

PIEZO1 Antibody (1081418) [Alexa Fluor® 488] Summary

• Immunogen: PIEZO1 containing synthetic peptide
  Accession # Q92508
• Specificity: Detects a synthetic peptide around aa 150 in Direct ELISA
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PIEZO1 Antibody (1081418) [Alexa Fluor® 488]

• FAM38A
• KIAA0233
• member A
• membrane protein induced by beta-amyloid treatment
• Mib
• PIEZO1
• piezo-type mechanosensitive ion channel component 1
• Protein FAM38A

Background

Piezo1 is an 287kDa mechanosensitive nonselective cation channel, extensively distributed in multiple tissues and cell types.  Piezo1 plays an important role in numerus physiological processes, such as determining vascular structure, urine osmoregulation, and blood pressure homeostasis.  In the kidney, Piezo1 expression is found in the renal corpuscle, convoluted tubules, and collecting ducts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.