PI4KB/PI4KIII beta Antibody

Western Blot: PI4KB/PI4KIII beta Antibody [NBP1-80907] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma and human liver tissue.

Immunohistochemistry-Paraffin: PI4KB/PI4KIII beta Antibody [NBP1-80907] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

PI4KB/PI4KIII beta Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: TLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENRIRSTRSVENLPECGITHEQRAGSFSTVPNYD
• Predicted Species: Mouse (100%), Rat (99%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PI4KB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  PI4KB/PI4KIII beta Protein (NBP1-80907PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PI4KB/PI4KIII beta Antibody

• DKFZp686O1820
• EC 2.7.1
• EC 2.7.1.67
• FLJ30129
• NPIK
• phosphatidylinositol 4-kinase, catalytic, beta
• PI4K92
• PI4KB
• PI4KB/PI4KIII beta
• PI4Kbeta
• PI4K-beta
• PI4KIII
• PI4KIIIBETA
• PIK4CB
• type III phosphatidylinositol 4-kinase beta
• wortmannin-sensitive

Background

Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PI4KB/PI4KIII beta Antibody (NBP1-80907)(1)

Publication using NBP1-80907

• Uzureau S, Lecordier L, Uzureau P et Al. APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin Cell Rep 2020-03-17 [PMID: 32187552] (WB, Human)

Bioinformatics

• Gene Symbol: PI4KB
• Entrez:
  • 5298(Human)
• Uniprot:
  • Q9UBF8(Human)