PHF8 Antibody (24GB945)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF
• Clone: 24GB945
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

PHF8 Antibody (24GB945) Summary

• Immunogen: A synthesized peptide derived from human PHF8 (Uniprot: Q9UPP1)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PHF8
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PHF8 Antibody (24GB945)

• EC 1.14.11.27
• histone lysine demethylase PHF8
• jumonji C domain-containing histone demethylase 1F
• KIAA1111
• KIAA1111ZNF422JHDM1F
• MRXSSD
• PHD finger protein 8DKFZp686E0868
• PHF8
• ZNF422

Background

PHF8 (PHD finger protein 8) is a member of the jumonji family of proteins and contains a jumonji C (JmjC) domain. The JmjC proteins are predicted to be metalloenzymes that play a role a chromatin remodeling and histone demethylation. PHF8 also bears a PHD (plant homeodomain)- type zinc-finger, a domain also found to be involved in chromatin remodeling and transcriptional regulation. Truncating mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate. PHF8 is also known as ZNF422 and KIAA1111.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PHF8