WB, IHC, IPHost:
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
PHF8 (PHD finger protein 8) is a member of the jumonji family of proteins and contains a jumonji C (JmjC) domain. The JmjC proteins are predicted to be metalloenzymes that play a role a chromatin remodeling and histone demethylation. PHF8 also bears a PHD (plant homeodomain)- type zinc-finger, a domain also found to be involved in chromatin remodeling and transcriptional regulation. Truncating mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate. PHF8 is also known as ZNF422 and KIAA1111.
|Product By Gene ID
- jumonji C domain-containing histone demethylase 1F
- histone lysine demethylase PHF8
- EC 22.214.171.124
- PHD finger protein 8DKFZp686E0868
Bioinformatics Tool for PHF8
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