Peroxiredoxin 6 Antibody (8H11)

Product Discontinued

Peroxiredoxin 6 Antibody (8H11) Summary

• Immunogen: Recombinant human 1-Cys peroxiredoxin.
• Specificity: 1-Cys-Peroxiredoxin (Prx VI).
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: PRDX6
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: Western Blot on rat lung lysate (24 kDa) or recombinant human protein. Immunohistochemistry on 4% paraformaldehyde fixed rat lung tissue. Immunocytochemistry/Immunofluorescence on rat type II alveolar epithelial cells.

Reactivity Notes

Human, Rat

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: No Preservative
• Purity: Unpurified

Notes

Relevant Entrez Gene Numbers: NM_004905.2

Alternate Names for Peroxiredoxin 6 Antibody (8H11)

• 1-Cys
• 24 kDa protein
• Acidic calcium-independent phospholipase A2
• aiPLA2
• aiPLA21-Cys PRX
• Antioxidant protein 2
• AOP2
• AOP2Non-selenium glutathione peroxidase
• EC 1.11.1.15
• EC 1.11.1.7
• EC 3.1.1.-
• KIAA0106Red blood cells page spot 12
• Liver 2D page spot 40
• MGC46173
• NSGPx
• NSGPx1-Cys peroxiredoxin
• p29
• Peroxiredoxin 6
• peroxiredoxin-6
• PRDX6
• PRX

Background

1-Cys-Peroxiredoxin is a cytosolic protein that is involved in the regulation of cellular redox potential. 1-Cys peroxiredoxin is a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities (Chen, 2000). It can reduce hydrogen peroxide, short chain fatty acids, and phospholipid hydroperoxides and is believed to play a role in phospholipid turnover as well as in the protection against oxidative injury.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRDX6
• Uniprot:
  • P30041()