Peroxiredoxin 6 Products

Antibodies
Peroxiredoxin 6 Antibody
Peroxiredoxin 6 Antibody
NBP2-19779
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Peroxiredoxin 6 Antibody
Peroxiredoxin 6 Antibody
AF3490
Species: Hu, Mu, Rt
Applications: WB
Host: Goat Polyclonal
Peroxiredoxin 6 Antibody (3A1 ...
Peroxiredoxin 6 Antibody (3A10-2A11)
H00009588-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
Peroxiredoxin 6 Overexpressio ...
Peroxiredoxin 6 Overexpression Lys...
NBL1-14743
Applications: WB
Proteins
Peroxiredoxin 6 Recombinant P ...
Peroxiredoxin 6 Recombinant Protein
NBP1-30188
Species: Hu
Applications: In vitro, PAGE
Peroxiredoxin 6 Recombinant P ...
Peroxiredoxin 6 Recombinant Protei...
NBP1-90332PEP
Species: Hu
Applications: AC
RNAi
Peroxiredoxin 6 RNAi
Peroxiredoxin 6 RNAi
H00009588-R01
Species: Hu

Description

FUNCTION: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. SUBUNIT: Homotetramer. May interact with HTR2A. SUBCELLULAR LOCATION: Cytoplasm. Lysosome. Note=Also found in lung secretory organelles. MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin. MISCELLANEOUS: Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress. SIMILARITY: Belongs to the ahpC/TSA family. Rehydrin subfamily.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 9588
Alternate Names
  • Antioxidant protein 2
  • EC 3.1.1.-
  • Acidic calcium-independent phospholipase A2
  • EC 1.11.1.7
  • p29
  • peroxiredoxin-6
  • PRX
  • EC 1.11.1.15
  • MGC46173
  • 24 kDa protein
  • 1-Cys
  • aiPLA21-Cys PRX
  • NSGPx1-Cys peroxiredoxin
  • KIAA0106Red blood cells page spot 12
  • AOP2Non-selenium glutathione peroxidase
  • Liver 2D page spot 40
  • peroxiredoxin 6

PTMs for Peroxiredoxin 6

Learn more about PTMs related to Peroxiredoxin 6.

Phosphorylation
Oxidation
Reduction
Acetylation
Formylation
Glutathionylation
Cleavage
Deamidation
Ubiquitination

Bioinformatics Tool for Peroxiredoxin 6

Discover related pathways, diseases and genes to Peroxiredoxin 6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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