Pentraxin 2/SAP Antibody (4F3)

Immunocytochemistry/Immunofluorescence: Pentraxin 2/SAP Antibody (4F3) [H00000325-M11] - Analysis of monoclonal antibody to APCS on HeLa cell. Antibody concentration 20 ug/ml

ELISA: Pentraxin 2/SAP Antibody (4F3) [H00000325-M11] - Detection limit for recombinant GST tagged APCS is approximately 3ng/ml as a capture antibody.

Product Discontinued

Pentraxin 2/SAP Antibody (4F3) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: APCS (AAH07058.1, 35 a.a. ~ 149 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VTDHVNLITPLEKPLQNFTLCFRAYSDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGTPLVKKGLRQGYFVEAQPK
• Specificity: APCS - amyloid P component, serum (4F3)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: APCS
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactivity against recombinant protein for WB. It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Pentraxin 2/SAP Antibody (4F3)

• 9.5S alpha-1-glycoprotein
• amyloid P component, serum
• APCS
• MGC88159
• Pentraxin 2
• PTX2
• PTX2serum amyloid P-component
• SAP
• SAPpentaxin-related
• Serum Amyloid P component

Background

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. This gene has multiple polyadenylation sites. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APCS
• Entrez:
  • 325(Human)
• Uniprot:
  • AAH07058(Human)