Pentraxin 2/SAP Products

Antibodies
Pentraxin 2/SAP Antibody [Unc ...
Pentraxin 2/SAP Antibody [Unconjug...
AF2558
Species: Hu, Mu
Applications: WB, Simple Western
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
Pentraxin 2/SAP Antibody (910 ...
Pentraxin 2/SAP Antibody (910119)
MAB1948
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Pentraxin 2/SAP Antibody
Pentraxin 2/SAP Antibody
AF1895
Species: Rt
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Human Pentraxin 2/SAP ELISA K ...
Human Pentraxin 2/SAP ELISA Kit (C...
KA1841
Species: Hu
Applications: ELISA
Mouse Pentraxin 2/SAP ELISA K ...
Mouse Pentraxin 2/SAP ELISA Kit
KA1976
Species: Mu
Applications: ELISA
Rat Pentraxin 2/SAP ELISA Kit ...
Rat Pentraxin 2/SAP ELISA Kit
KA1934
Species: Rt
Applications: ELISA
Lysates
Pentraxin 2/SAP Overexpressio ...
Pentraxin 2/SAP Overexpression Lys...
NBL1-07596
Species: Hu
Applications: WB
Proteins
Recombinant Human Pentraxin 2 ...
Recombinant Human Pentraxin 2/SAP ...
1948-SA
Species: Hu
Applications: Bind
Recombinant Mouse Pentraxin 2 ...
Recombinant Mouse Pentraxin 2/SAP ...
2558-SA
Species: Mu
Applications: Bind
Recombinant Rat Pentraxin 2/S ...
Recombinant Rat Pentraxin 2/SAP Pr...
1895-SA
Species: Rt
Applications: Bind
RNAi
Pentraxin 2/SAP RNAi
Pentraxin 2/SAP RNAi
H00000325-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Serum Amyloid P (SAP) is a non-fibrillar plasma glycoprotein that belongs to the pentraxin family. It is universally found in amyloid deposits and this is probably due to its specific calcium-dependent binding to motifs present on all types of amyloid fibrils. SAP is also found to prevent fibrillar breakdown by enzymes and it is believed that it helps maintains stability of the amyloid deposits (1,2). It has been shown that SAP binds monocytes with high avidity, but does not bind to erythrocytes, NK cells, T lymphocytes or B lymphocytes (3). SAP production can be induced by exposure to IL-1, IL-6 and IFN-beta. The SAP-inducing activity was neutralized by antibodies to each of the recombinant cytokines (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 325
Alternate Names
  • MGC88159
  • PTX2serum amyloid P-component
  • SAPpentaxin-related
  • 9.5S alpha-1-glycoprotein
  • amyloid P component, serum

Bioinformatics Tool for Pentraxin 2/SAP

Discover related pathways, diseases and genes to Pentraxin 2/SAP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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