Pentraxin 2/SAP Products

Antibodies
Pentraxin 2/SAP Antibody [Unc ...
Pentraxin 2/SAP Antibody [Unconjug...
AF2558
Species: Hu, Mu
Applications: WB, Simple Western
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
Pentraxin 2/SAP Antibody
Pentraxin 2/SAP Antibody
NBP2-31392
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Pentraxin 2/SAP Antibody
Pentraxin 2/SAP Antibody
AF1895
Species: Rt
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Pentraxin 2/SAP ELISA Kit [Bi ...
Pentraxin 2/SAP ELISA Kit [Biotin]
KA1841
Species: Hu
Pentraxin 2/SAP ELISA Kit [HR ...
Pentraxin 2/SAP ELISA Kit [HRP]
KA1934
Species: Rt
Pentraxin 2/SAP ELISA Kit [HR ...
Pentraxin 2/SAP ELISA Kit [HRP]
KA1976
Species: Mu
Lysates
Pentraxin 2/SAP Overexpressio ...
Pentraxin 2/SAP Overexpression Lys...
NBL1-07596
Applications: WB
Proteins
Pentraxin 2/SAP Recombinant P ...
Pentraxin 2/SAP Recombinant Protei...
NBP2-31392PEP
Species: Hu
Applications: AC
Pentraxin 2/SAP Partial Recom ...
Pentraxin 2/SAP Partial Recombinan...
H00000325-Q01
Species: Hu
Applications: WB, ELISA, PA
Pentraxin 2/SAP Partial Recom ...
Pentraxin 2/SAP Partial Recombinan...
H00000325-Q02
Species: Hu
Applications: WB, ELISA, PA
RNAi
Pentraxin 2/SAP RNAi
Pentraxin 2/SAP RNAi
H00000325-R01
Species: Hu

Description

Serum Amyloid P (SAP) is a non-fibrillar plasma glycoprotein that belongs to the pentraxin family. It is universally found in amyloid deposits and this is probably due to its specific calcium-dependent binding to motifs present on all types of amyloid fibrils. SAP is also found to prevent fibrillar breakdown by enzymes and it is believed that it helps maintains stability of the amyloid deposits (1,2). It has been shown that SAP binds monocytes with high avidity, but does not bind to erythrocytes, NK cells, T lymphocytes or B lymphocytes (3). SAP production can be induced by exposure to IL-1, IL-6 and IFN-beta. The SAP-inducing activity was neutralized by antibodies to each of the recombinant cytokines (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 325
Alternate Names
  • MGC88159
  • PTX2serum amyloid P-component
  • SAPpentaxin-related
  • 9.5S alpha-1-glycoprotein
  • amyloid P component, serum

Bioinformatics Tool for Pentraxin 2/SAP

Discover related pathways, diseases and genes to Pentraxin 2/SAP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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