Recombinant Human PDRG1 His Protein

SDS-Page: Recombinant Human PDRG1 Protein [NBP1-50871] - 15 % SDS-PAGE (3ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human PDRG1 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-133 of Human PDRG1
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: PDRG1
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 17.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 0.2 M NaCl, 5mM DTT, 20% glycerol
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human PDRG1 His Protein

• C20orf126p53 and DNA damage regulated 1
• chromosome 20 open reading frame 126
• dJ310O13.3
• p53 and DNA-damage regulated 1
• PDRGp53 and DNA damage-regulated protein 1

Background

PDRG1, also known as PDRG or C20orf126, is a 133 amino acid protein that localizes to the cytoplasm and belongs to the prefoldin subunit beta family. Expressed predominately in normal testicular tissue, PDRG1 is functionally induced by ultraviolet light and is thought to play a role in chaperone-mediated protein folding, possibly playing a role in cellular degradation. It is associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Recombinant human PDRG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: PDRG1