PDLIM5 Antibody

Product Discontinued

PDLIM5 Antibody Summary

• Immunogen: PDLIM5 (AAH08741, 1 a.a. ~ 596 a.a) full length recombinant protein with GST tag.MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPT
• Specificity: PDLIM5 - PDZ and LIM domain 5
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: PDLIM5
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human, Mouse.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PDLIM5 Antibody

• Enh
• ENH1
• ENHLIM
• Enigma homolog
• enigma-like LIM domain protein
• Enigma-like PDZ and LIM domains protein
• PDZ and LIM domain 5
• PDZ and LIM domain protein 5

Background

The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PDLIM5 Antibody (H00010611-A02)(2)

Publications using H00010611-A02

• Schliekelman MJ, Gibbons DL, Faca VM et al. Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. Cancer Research. 2011-10-10 [PMID: 21987723]
• Cheng H, Kimura K, Peter AK et al. Loss of Enigma Homolog Protein Results in Dilated Cardiomyopathy. Circ Res. 2010-06-10 [PMID: 20538684]

Bioinformatics

• Gene Symbol: PDLIM5
• Entrez:
  • 10611(Human)
• OMIM:
  • 605904(Human)
• Uniprot:
  • AAH08741(Human)