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PARN Antibody

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Summary
Product Discontinued
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    • Catalog Number
      NBP2-04118
    • Availability
      Product Discontinued

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PARN Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 539 and 589 of human Poly(A)-Specific Ribonuclease (Deadenylation Nuclease) using the numbering given in entry NP_002573.1 (GeneID 5073).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PARN
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2-10 mcg/mg
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PARN Antibody

  • DANEC 3.1.13.4
  • Deadenylating nuclease
  • Deadenylation nuclease
  • poly(A)-specific ribonuclease (deadenylation nuclease)
  • poly(A)-specific ribonuclease PARN
  • Polyadenylate-specific ribonuclease

Background

Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. The amino acid sequence of poly(A)-specific ribonuclease shows homology to the RNase D family of 3'-exonucleases. The protein appears to be localized in both the nucleus and the cytoplasm. It is not stably associated with polysomes or ribosomal subunits.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PARN
Uniprot