Pannexin-2 Antibody (719406) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB
• Clone: 719406
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

Pannexin-2 Antibody (719406) [mFluor Violet 450 SE] Summary

• Immunogen: E. coli-derived recombinant human Pannexin-2
  Arg316-Lys456
  Accession # Q96RD6
• Specificity: Detects human Pannexin-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human (rh) Pannexin-1 and no cross-reactivity with rhPannexin-3 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PANX2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Pannexin-2 Antibody (719406) [mFluor Violet 450 SE]

• hPANX2
• MGC119432
• pannexin 2
• Pannexin2
• Pannexin-2
• PANX2
• PX2

Background

The protein encoded by the Pannexin 2 gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PANX2