PAK7 Antibody (444703) [Alexa Fluor® 488]

• Reactivity: Hu, Rt
• Applications: WB, IHC
• Clone: 444703
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

PAK7 Antibody (444703) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human PAK7
  Met1-Glu134
  Accession # Q9P286
• Specificity: Detects human and rat PAK7 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PAK5
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PAK7 Antibody (444703) [Alexa Fluor® 488]

• PAK5
• PAK7

Background

PAK7 (p21-activated kinase 7), also called PAK5, is a neuronal member of the PAK-II subfamily within the STE Ser/Thr protein kinase family. In the portion used as immunogen, human PAK7 shares 95% aa sequence identity with rat PAK7. This portion contains a CDC42/Rac1 interactive binding (CRIB) motif and potential phosphorylation sites at Ser104 and Thr107. In addition, PAK7 also interacts with RhoD and RhoH, directing its subcellular localization. PAK7 can be located in the mitochondrion, where it protects cells from apoptosis, or in the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PAK5