PACE4/PCSK6 Antibody - BSA Free

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Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP3-14443] - PACE4/PCSK6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ca, Eq, Pm, Pm, RbSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

PACE4/PCSK6 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 14 amino acid peptide from Cys-rich motif (CRM) region of human PACE4/PCSK6.
Epitope
Internal
Specificity
Human PACE4/PCSK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (93%), Rat (100%), Canine (93%), Primate (100%), Equine (100%), Monkey (100%), Rabbit (100%), Bovine (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
PCSK6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K..

Reactivity Notes

Expected reactivity based on percent sequence identity: Turkey, Chicken (86%)

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PACE4/PCSK6 Antibody - BSA Free

  • EC 3.4.21
  • EC 3.4.21.61
  • EC 3.4.21.75
  • PACE4
  • PACE4/PCSK6
  • PACE4EC 3.4.21.-
  • Paired basic amino acid cleaving enzyme 4
  • paired basic amino acid cleaving system 4
  • PCSK6
  • Proprotein Convertase 6
  • proprotein convertase subtilisin/kexin type 6
  • SPC4
  • SPC4subtilisin-like protease
  • Subtilisin/kexin-like protease PACE4
  • Subtilisin-like proprotein convertase 4

Background

The protein encoded by the PACE4 gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PCSK6