Otoraplin/OTOR Antibody [Alexa Fluor® 488]

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

Otoraplin/OTOR Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human Otoraplin/OTOR
  Val18-Glu128
  Accession # Q9NRC9
• Specificity: Detects human and mouse Otoraplin/OTOR in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Otoraplin/OTOR Antibody [Alexa Fluor® 488]

• FDPMelanoma inhibitory activity-like protein
• Fibrocyte-derived protein
• MGC126739
• MIAL1
• MIALMGC126737
• OTOR
• Otoraplin

Background

Otoraplin (OTOR), also known as fibrocyte-derived protein (Fdp) and Melanoma inhibitory activity-like (MIAL), is a secreted 16 kDa globular protein that is preferentially expressed in the inner ear by periotic mesenchyme and developing and mature fibrocytes. It is highly homologous to MIA/cartilage-derived retinoic acid‑sensitive protein (CD-RAP), which is a cartilage-specific protein that is also expressed in malignant melanoma cells. The 111 amino acid residue (aa) mature human otoraplin contains one SH3 domain (aa 46‑107) and a Tyr at position 50 that is reportedly sulfated. Otoraplin is reported to play a role in the initiation of periotic mesenchyme chondrogenesis. Mature human Otoraplin shares 91% and 89% aa sequence identity with canine and mouse Otoraplin, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.