Recombinant Human Osteocrin Protein

Product Discontinued

Recombinant Human Osteocrin Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 28-133 of Human Osteocrin
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MVDVTTTEAF DSGVIDVQST PTVREEKSAT DLTAKLLLLD ELVSLENDVI ETKKKRSFSG FGSPLDRLSA GSVDHKGKQR KVVDHPKRRF GIPMDRIGRN RLSNSRG

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: OSTN
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 14 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 20% glycerol, 200 mM NaCl
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >95% pure by SDS-PAGE

Alternate Names for Recombinant Human Osteocrin Protein

• Musclin
• Osteocrin
• OSTN

Background

Osteocrin (OSTN), also known as Musclin, contains two conserved sequence motifs homologous to the natriuretic peptide family. This protein appears to modulate osteoblastic differentiation and highly expressed in cells of osteoblast lineage and in skeletal muscle tissue. It could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. Recombinant human OSTN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: OSTN